Oxford University's COVID-19 Vaccine is Highly Effective
The Covid_19 vaccine developed by the University of Oxford is highly effective at stopping people developing Covid-19 symptoms,a large trial shows....!
(Courtesy by BBC) (Prepared by Ramzan Awan)
The results will be seen as a triumph, but come after Pfizer and Moderna vaccines showed 95% protection...!
While the Oxford jab is far cheaper,& is easier to store and get to every corner of the world than the other two...!
So the vaccine will play a significant role in tackling the pandemic, if it is approved for use by regulators...!
Today's announcement takes us another step closer to the time when we can use vaccines to bring an end to the devastation caused by the virus said the vaccine's architect, Prof Sarah Gilbert...!
The UK government has pre-ordered 100 million doses of the Oxford vaccine,& AstraZeneca says it will make three billion doses for the world next year...!
UK's Prime Minister Boris Johnson said it was incredibly exciting news & that while there were still safety checks to come,these are fantastic results...!
Speaking at a Downing Street briefing on Monday evening,Mr Johnson added that the majority of people most in need of a vaccination in the UK might be able to get one by Easter...!
& Prof Andrew Pollard - director of the Oxford vaccine group - said it had been a very exciting day & paid tribute to the 20,000 volunteers in the trials around the world, including more than 10,000 in the UK...!
What did the trial show?
The vaccine has been developed in around 10 months,a process that normally takes a decade
There are two results from the trial of more than 20,000 volunteers in the UK and Brazil...!
Overall,there were 30 cases of Covid in people who had two doses of the vaccine and 101 cases in people who received a dummy injection.The researchers said it worked out at 70% protection, which is better than the seasonal flu jab...!
Nobody getting the actual vaccine developed severe-Covid or needed hospital treatment...!
The trial's lead investigator,it was really pleased with the results as it means we have a vaccine for the world...!
While protection was 90% in an analysis of around 3,000 people on the trial who were given a half-sized first dose and a full-sized second dose...!
Prof Pollard said the finding was intriguing & would mean we would have a lot more doses to distribute...!
The analysis also suggested there was a reduction in the number of people being infected without developing symptoms, who are still thought to be able to spread the virus...!
When will I get a vaccine?
In the UK there are four million doses of the Oxford vaccine ready to go. But nothing can happen until the vaccine has been approved by regulators who will assess the vaccine's safety, effectiveness,& that it is manufactured to high standard.This process will happen in the coming weeks...!
It is also unclear who will get this vaccine or the other vaccines the government has ordered...!
While the UK is preparing to press the go button on an unprecedented mass immunisation campaign that dwarfs either the annual flu or childhood vaccination programmes...!
Care home residents & staff will be first in the queue, followed by healthcare workers and the over-80s. The plan is to then to work down through the age groups...!
How does it work?
It uses a completely different approach to the vaccines from Pfizer & Moderna, which inject part of the virus's genetic code into patients...!
The Oxford vaccine is a genetically modified common cold virus that used to infect chimpanzees...!
It has been altered to stop it causing an infection in people and to carry the blueprints for part of the coronavirus, known as the spike protein...!
Once these blueprints are inside the body they start producing the coronavirus spike protein, which the immune system recognizes as a threat & tries to squash it...!
When the immune system comes into contact with the virus for real,it will know what to do...!
Why is the low dose better?
There is not a straightforward answer...!
One idea is the immune system rejects the vaccine,which is built around a common cold virus,if it is given in too big an initial dose...!
Or a low then high shot may be a better mimic of a coronavirus infection & lead to a better immune response...!
Are the results disappointing?
After Pfizer and Moderna both produced vaccines delivering 95% protection from Covid-19, a figure of 70% is still highly effective, but will be seen by some as relatively disappointing...!
But this is still a vaccine that can save lives from Covid-19 and is more effective than a seasonal flu jab...!
It also has crucial advantages that make it easier to use.It can be stored at fridge temperature, which means it can be distributed to every corner of the world, unlike the Pfizer/BioNTech and Moderna vaccines, which need to be stored at much colder temperatures...!
The Oxford vaccine,at a price of around £3, also costs far less than Pfizer's (around £15) or Moderna's (£25) vaccines...b
The Oxford technology is more established,so the vaccine is easier to mass produce cheaply.AstraZeneca has also made a no-profit pledge...!
What difference will this make to my life?
A vaccine is what we've spent the year waiting for & what lockdowns have bought time for...!
While producing enough vaccine & then immunising tens of millions of people in the UK, & billions around the world, is still a gargantuan challenge...!
Life will not return to normal tomorrow,but the situation could improve dramatically as those most at risk are protected...!
Health Secretary Matt Hancock told that we would be something closer to norma by the summer but until we can get that vaccine rolled out,we all need to look after each other...!
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